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Rhode Island Woman Claims Fosamax Caused Painful Thigh Break

Merck is facing yet another Fosamax lawsuit. This time, the national law firm, Parker Waichman LLP, filed a lawsuit on behalf of a woman who took Fosamax (alendronate) and suffered a right femur fracture, allegedly due to the bone loss medication.

Prescribed to fight bone loss in patients with osteoporosis and other conditions, the bisphosphonate drug has been linked to increased risk of atypical femur fractures. The law suit names Merck Sharp & Dohme Corp. and Merck & Co. as defendants. (more…)

Indiana Woman Claims Fosamax Caused Two Femur Fractures

Yet another woman has come forward to say that Fosamax (alendronate) caused her two femur fractures. The national law firm, Parker Waichman LLP, just filed a lawsuit on behalf of an Indiana woman who suffered a left and right femur fracture after taking Fosamax.

Fosamax, an oral bisphosphonate, is in a class of drugs that the U.S. Food & Drug Administration (FDA) says may not provide any long-term benefits, while simultaneously increasing risks for atypical femur fractures. The lawsuit names Merck Sharp & Dohme Corp., Merck & Co., Inc, and other potential manufacturers as defendants and was filed on June 29th in the Superior Court of New Jersey, Atlantic County Law Division (Case No. L-4565-12). (more…)

First-Time Bisphosphonate Users At Risk For Eye Diseases

First-time bisphosphonate users are at increased risk for eye diseases, according to an emerging study. Fosamax and Actonel are two of the most popularly prescribed drugs in this class and are used in the treatment of osteoporosis.

The inflammatory eye diseases—anterior uveitis and sleritis—can lead to significant vision impairment, according to case reports, said Philly.com. The study appears in the April 2 issue of the journal Canadian Medical Association Journal (CMAJ). Uveitis is inflammation of the eye’s middle layer; rarely, this can lead to blindness. Scleritis is inflammation of the eye’s outer wall. (more…)

FDA Panel Backs Limits on Osteoporosis Drugs

An advisory committee to the U.S. Food and Drug Administration (FDA) has suggested the agency limit how long patients can remain on bisphosphonate therapy for their osteoporosis. The committee was unable, however, to agree on what that limit should be, said ABC News.

The Advisory Committee for Reproductive Health Drugs and the Drug Safety and Risk Management Advisory Committee discussed if the FDA should change its label to indicate that the drugs should not be used long term. The Committee agreed a label change is in order, but, despite 17-to-6 votes for, said ABC News, the Committee was unable to agree on a timeframe, claiming insufficient data. (more…)

Osteoporosis Drugs Like Fosamax Can Stop After Five Years

Following its review of Fosamax, the U.S. Food and Drug Administration (FDA) has determined that women taking Fosamax and other bone strengthening medications known as oral bisphosphonates can, for the most part, safely stop taking the drugs within five years.

According to the FDA staff report, said the New York Times, which has been released prior to meeting of two of its scientific advisory committees, research reveals that while osteoporosis medications offer benefits in fracture prevention in the first three years of treatment, the benefits diminish after five years. As a matter-of-fact, continuing to take medications such as Fosamax after five years does not offer benefits over no drug treatment, according to the report, said the Times. (more…)

Fosamax, Other Bone Drugs Set for FDA Review

Drugs called oral bisphosphonates, including Merck & Co.’s osteoporosis medication Fosamax, are scheduled for review by a U.S. Food and Drug Administration (FDA) advisory panel over concerns about serious adverse events. Among other things, the panel will recommend whether or not long-term used of the drugs should be limited due to their association with a rare type of femur fracture.

It was once believed that Fosamax and similar medications could be taken indefinitely. Oral bisphosphonates are widely used in the treatment of post-menopausal women at risk for osteoporosis,especially those diagnosed with low bone density, said the Wall Street Journal.Oral bisphosphonates are also prescribed for the treatment of bone diseases such as Paget’s disease. Other drugs in this class include Actonel, Boniva, Atelvia, Didronel, and Skelid. (more…)

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