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Another Metal-On-Metal Hip Study Sees Early Failures | cialis online

Another Metal-On-Metal Hip Study Sees Early Failures

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Another study has revealed a high rate of early failures associated with metal-on-metal hip implants. The medical devices have been linked to a growing number of problems, including early failure rates and adverse medical reactions.

According to the new study, all-metal devices “should not be implanted,” and the “world’s largest register of hip implants” reveals “unequivocal evidence” of the unusually high failure rates, said the BBC. The greatest risks were seen in women, younger patients, and involving large implant devices.

Being described as the most comprehensive study of its kind, to date, the research, published in The Lancet, involved a University of Bristol analysis that reviewed data from the National Joint Registry of England and Wales that involved over 400,000 hip devices—31,171 were all-metal—implanted from 2003 to 2011, said the BBC.

The research revealed that patients outfitted with metal-on-metal hip implants suffered a two-fold likelihood of undergoing early device failure versus people fitted with different types of devices. U.K.’s health regulator has recently recommended annual checks for people implanted with large head metal-on-metal hip replacements. Hip devices can be all metal, all ceramic, or metal-on-plastic.

The study found that, overall, 6.2% of metal-on-metal hips failed within five years, versus only 1.7% of metal-on-plastic and 2.3% of ceramic-on-ceramic hip devices, said the BBC. Women experienced the greatest failure rates. “Revision rates for stemmed metal-on-metal implants in women were up to four-times higher,” while men were three times likelier to require a replacement, said the team, wrote the BBC. Increases in failure rates increased with larger implants. For instance, said the study researchers, “each 1mm increase in head size being associated with a 2% increase” in the risk of revision, the researchers wrote. Conversely, ceramic implants performed better as the device’s head size increased, said the BBC.

Dr. Art Sedrakyan, from the Weill Cornell Medical College, pointed out that “When failures take a long time to develop, many faulty products can enter the market. We are left with more than 500,000 patients with metal-on-metal prostheses in the USA and more than 40,000 in the UK who are elevate risk of device failure, which will inevitably result in the burden of further surgical treatment,” wrote the BBC.

The researchers added that “Metal-on-metal stemmed articulations give poor implant survival compared with other options and should not be implanted…. All patients with these bearings should be carefully monitored, particularly young women implanted with large diameter heads,” the BBC reported.

This is not the first time health risks and high failure rates have been linked to all-metal hip implants. Last month, the British Medical Journal wrote that metal-on-metal hip implant manufacturers were long aware of growing evidence linking metal-on-metal hip replacement devices to serious, long-term health issues, but never advised consumers about the issue.

Metal-on-metal hip implants include DePuy Orthopaedics’ ASR Hip Resurfacing System and the DePuy ASR Acetabular System—both recalled in 2010 over significantly high early failure rates. To date, DePuy, a unit of Johnson & Johnson, is looking at over 5,000 U.S. lawsuits over its defective ASR implants; no less than 900 lawsuits have been filed in the U.S. over an all-metal version of its Pinnacle hip replacement device, which plaintiffs claim is similar in design to the faulty ASRs and should have, but weren’t recalled.

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