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Pancreas Issues Have Doctors Wary Of Byetta, Januvia | cialis online

Pancreas Issues Have Doctors Wary Of Byetta, Januvia

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Pancreatitis has doctors concerned with the medications Byetta and Januvia, drugs used in the treatment of Type 2 diabetes. A recent syndicated, impact-assessment study has raised some issues regarding the medications and has doctors wary of prescribing the drugs. The study, conducted by dtw Marketing Research Group, Inc., was published in the American Gastroenterology Association Journal, said PharmaLive.

As NewsInferno wrote, the controversy was sparked by research that indicated that medications like Byetta and Januvia might raise risks for pancreatic cancer and pancreatitis. The makers of the drugs continue to maintain the medications are safe.

The medical study, published in the journal Gastroenterology, was based on an analysis of reports made to the U.S. Food & Drug Administration’s (FDA) Adverse Event Reporting (AER) Database between 2004 and 2009. While the study’s findings do not prove that either drug causes cancer, the data raised concerns that they and other GLP-1 therapies, including Victoza, could raise cancer risks, said NewsInferno..

Both Januvia and Byetta lower diabetic blood sugar levels by promoting the action of the hormone glucagon-like peptide 1 (GLP-1) in the gut. This summer’s study revealed that use of either Byetta or Januvia, was linked with a six-fold increased risk for developing pancreatitis, versus other treatments. The study also revealed tat the pancreatic cancer event rate 2.9-fold greater in those patients taking Byetta and 2.7-fold greater in patients taking Januvia versus other treatments.

PharmaLive wrote that, based on the early results from the impact-assessment study, some doctors are questioning their use of Byetta, a glucagon-like peptide-1 mimetic and Januvia, a dipeptidyl peptidase−4 inhibitor sitagliptin (Januvia). About 11-20% of endocrinologists and primary care physicians surveyed indicated that they might decrease their use of the drugs in the future. About 29-30% of the doctors surveyed said that they intend on letting their patients know about the emerging issues concerning Byetta and Januvia, wrote PharmaLive.

This research, said PharmaLive, which tracked endocrinologists and primary care physicians, was conducted November 10-16, 2011, and involved 104 respondents comprised of 52 endocrinologists and 52 primary care physicians.

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