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Chantix Needs Stronger Warnings, Researchers Say | cialis online

Chantix Needs Stronger Warnings, Researchers Say

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Researchers are urging federal regulators impose stronger Chantix warnings, citing suicidal behaviors and depression. Chantix (varenicline) is Pfizer’s highly controversial stop smoking medication.

Scientists say that the U.S. Food and Drug Administration (FDA) needs to strengthen Chantix label based on adverse psychological behaviors that appear in greater frequency than other quit smoking medications and methods, said ABC News.

Approved in 2006, Chantix has been the source of safety debates after being implicated in a number of suicides, episodes of suicidal ideation, and other adverse and strange behaviors. In July, said NewsInferno, the Chantix label was updated for patients with pre-existing heart disease and chronic obstructive pulmonary disease (COPD).

Although experts have raised issues since 2007 concerning links between Chantix and cardiovascular and vision problems, emerging studies have pointed to increases in depression and suicidal thoughts, noted ABC News. Patients have discussed vivid, “wild” dreams; unexplained violent behaviors; and other ‘psychological disturbances,” while taking Chantix, said ABC News.

In 2009, a “black box” warning label—the FDA’s strongest—was included on Chantix and the drug, Zyban, warning physicians and patients about increased risks for depression, violence, and suicidal thinking, said ABC News. Some experts say these warnings are insufficient and, this week a study published in the journal PLos One, warned readers about Chantix and urged the agency to update the warning label to state that the psychological risks linked to Chantix are more that those of nicotine replacement drugs and of its competition, Zyban, said ABC News.

Dr. Curt Furberg, a professor of public health sciences at Wake Forest Baptist Medical Center and one of the study’s authors, noted that people trying to quit smoking tend to be at greater risk for psychological symptoms, said ABC News. Dr. Furberg stressed that Chantix increases those risks. “The dramatic increase of these symptoms is caused by the drug. Among all the treatments we have for smoking cessation, Chantix is the worst,” he said, wrote ABC News.

The researchers reviewed over 3,000 reports—submitted through the FDA’s Adverse Event Reporting System from 1998 to 2010—of suicidal behaviors or depression in people taking Chantix, Zyban, or nicotine replacement drugs, said ABC News. Of the reports, 90 percent were linked to Chantix; 92 percent of completed suicides reported were linked to Chantix. “The FDA’s own data show that Chantix is more dangerous than other treatments to stop smoking,” Furberg noted, reported ABC News. Both the FDA and Pfizer remain unfazed.

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