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Group Issues Warning On Avodart, Proscar | cialis online

Group Issues Warning On Avodart, Proscar

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Public Citizen is advising consumers against using certain 5-Alpha Reductase Inhibitors (5-ARIs)— Proscar (finasteride) and Avodart (dutasteride)—for enlarged prostate.

Avodart was approved for treatment of enlarged prostate in November 2001 by the U.S. Food and Drug Administration (FDA), said Public Citizen’s latest issue of Worst Pill, Best Pill. Propecia, another 5-ARI, also contains finasteride and is use to treat male baldness.

This summer, the FDA warned that 5-ARIs were linked to a higher risk of high-grade prostate cancer. The FDA said two large studies revealed that while 5-ARIs reduced the overall risk of prostate cancer, they increased the risk for development of the more serious high-grade tumor.

The Worst Pills, Best Pills article suggests that due to increased risks of serious prostate cancer, Avodart and Proscar should not be used for their approved uses and that safer alternatives should be considered.

Enlarged prostate, also known as benign prostatic hypertrophy (BPH) or benign prostatic hyperplasia, is a common disorder in which the male prostate gland becomes enlarged with age, explained Worst Pill, Best Pill. Treatment depends on if urinary symptoms are present. Urinary symptoms—due to a partial urethra obstruction which thickens the bladder, causing it to hold less urine—include a hesitant, interrupted, or weak urine stream; urgency, leaking, or dribbling; and more frequent urination.

Worst Pills, Best Pills suggest that alpha blockers – alfuzosin (UROXATRAL), prazosin (MINIPRESS), tamsulosin (FLOMAX), terazosin (HYTRIN) or doxazosin (CARDURA) – ae safer alternatives to 5-ARIs. The article also pointed out that surgery is a possible treatment for BPH.

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